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Intermediates & Side Chains

Sr. no.

Intermediate

CAS No.

Structure

End use

Pharma Intermediates

1

CMIC Chloride
3-(2-Chlorophenyl)-5-methyl isoxazole-4-carbonyl chloride

25629-50-9


MF:C11H7Cl2NO2
MW: 256.08

Cloxacillin

2

DCIMC Chloride
3-(2,6 Dichlorophenyl)-5-methyl isoxazole-4-carbonyl chloride

4462-55-9


MF:C11H6Cl3NO2
MW: 290.53

Dicloxacillin

3

FCIMC Chloride
3-(2-Chloro-6-fluorophenyl)-5-methyl isoxazole-4-carbonyl chloride

69399-79-7


MF:C11H6Cl2FNO2
MW: 274.07

Flucloxacillin

4

PMIC Chloride
3-Phenyl-5-methyl isoxazole-4-carbonyl chloride

16883-16-2


MF:C11H8ClNO2
MW: 221.64

Oxacillin

5

EDPCC
4-Ethyl-2,3-dioxo-piperazine carbonyl chloride

59703-00-3


MF: C7H9ClN2O3
MW: 204.61

Piperacillin

6

EPCP
(R)-[[(4-Ethyl-2,3-dioxopiperazin-1 -yl) carbonyl]amino]phenylacetic acid

63422-71-9


MF:C15H17N3O5
MW: 319.31

Piperacillin

7

(3R,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy) ethyl]azetidin-2-one

76855-69-1


MF: C13H25NO4Si
MW: 287.43

Carbapenem

8

Azacyclonol base
alpha,alpha-Diphenyl-4- piperidinomethanol hydrochloride

115-46-8


MF: C18H21NO
MW: 267.37084

Fexofenadine

9

Isonipecotic acid
4-Piperidinecarboxylic acid

498-94-2


MF: C6H11NO2
MW: 129.16

Fexofenadine, Risperidone

10

GMC - X12 2-Deoxy-2,2-diflouro-D-erythro-pentafuranose-1-ulose-3,5-dibenzoate

122111-01-7


MF: C19H14F2O6
MW: 376.313366

Gemcitabine HCl

11

Lm3 [1R-[1-a(2S*,5R*),2B,5B]]-5- (4-Amino-2-oxo-1(2H)- pyrimidinyl)-1,3-oxathiolane-2- carboxylic acid- 5-methyl-2- (1-methylethyl)cyclohexyl ester

147126-73-6


MF: C18H27N3O4S
MW: 381.49

Lamivudine

12

1-(4-Azido-5-trityloximethyl- tetrahydrofuran-2-yl)-5-methyl- 1H-pyrimidine-2,4-dione

29706-84-1


MF: C29H27N5O4
MW: 509.57

Zidovudine

13

4-Methyl-10-trityloxymethyl-8, 11-dioxa-2,6-diaza-tricyclo [7.2.1.0*2,7*] dodec-6-en-5-one OR 3-Azido-3-Deoxy-5-O- Triphenylmethylthymidine

25442-42-6


MF: C29H28N2O4
MW: 466.52

Zidovudine

14

DKT3 4-Fluoro-A-(2-methyl-1- oxopropyl)- r-oxo-N,B-diphenyl benzene butanamide

125971-96-2


MF: C26H24FNO3
MW: 417.47

Atorvastatin Calcium

15

ATS-5 (R)-4-Cyano-3- hydroxybutyric acid ethyl ester (R)-4-Cyano-3- hydroxybutyric acid ethyl ester

141942-85-0


MF: C7H11NO3
MW: 157.17

Atorvastatin Calcium

16

ATS-8 (4R,cis)-1,1-Dimethylethyl-6- cyanomethyl-2,2-dimethyl-1, 3-dioxane-4-acetate

125971-94-0


MF: C14H23NO4
MW: 269.34

Atorvastatin Calcium

17

ATS-9 (4R,cis)-1,1-Dimethylethyl-6- aminoethyl-2,2-dimethyl-1, 3-dioxane-4-acetate

125995-13-3


MF: C14H27NO4
MW: 273.37

Atorvastatin Calcium

18

ATV-1 tert-Butyl (4R,6R)-2-[[[6- (2-4-fluorophenyl)-5-isopropyl- 3-phenyl-4-(phenylcarbamoyl)- pyrrol-1-yl]ethyl]-2,2-dlmethyl-1, 3-dioxan-4-yl]acetate

125971-95-1


MF: C40H47FN2O5
MW: 654.81

Atorvastatin Calcium

19

(S)-2-(2-Amino-5-chlorophenyl)- 4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol

209414-27-7


MF: C13H14ClNO
MW: 235.72

Efavirenz

20

Ethyl 4-chloro acetoacetate

638-07-3


MF:C6H9ClO3
MW: 164.59

Amlodipine

21

Ethyl 4-(2-(1,3-dioxoisoindolin- 2-yl)ethoxy)-3-oxobutanoate

88150-75-8


MF: C16H17NO6
MW: 319.32

Amlodipine

22

Phthaloyl amlodipine
3-Ethyl-5-methyl-4-(2-chlorophenyl)-2- (2-phthalimidoethoxy)-methyl-6- methyl-1,4-dihydropyridine-3,5- dicarboxylate

88150-62-3


MF: C28H27ClN2O7
MW: 538.98

Amlodipine

23

4,5,6,7-Tetrahydrothieno[3,2-c] pyridine hydrochloride

28783-41-7


MF: C7H9NS.HCl
MW: 175.72

Clopidogrel, Ticlopidine

24

Coupled amine Hcl S-(+)-Methyl-2 (2-thienylethylamino)-2- (2-chlorophenyl) acetate HCl / D-(+)-Methyl-alpha- (2-thienylethamino) (2-Chlorophenyl) acetate hydrochloride.

141109-19-5


MF: C15H16ClNO2S.HCl
MW: 346.27

Clopidogrel

25

Clopidogrel base S-(2-Chloro-phenyl)- (6,7-dihydro-4H-thieno [3,2-c]pyridin-5-yl)-acetic acid methyl ester

113665-84-2


MF: C16H16ClNO2S
MW: 321.82

Clopidogrel

26

S (-)-3-(Dimethylamino)-1- (thiophen-2-yl)propane-1-ol

132335-44-5


MF: C9H15NOS
MW: 185.29

Duloxetine

27

S(-)-3-(Methylamino)-1- (thiophen-2-yl)propane-1-ol

116539-55-0
116539-56-1


MF: C8H13NOS
MW: 171.29

Duloxetine

28

S (+) - N,N-Dimethyl-3- (naphthalen-l-yloxy)-3- (thiophen-2-yl) propan-1-amine base and oxalate

132335-47-8
(Oxalate)
132335-46-7
(Base)


MF: C19H21NOS.C2H2O4
MW: 401.48

Duloxetine

29

DIOL (S)-1-[[[1-[3-[2-(7-Chloro-2-quinolinyl) ethenyl] phenyl]]-3-[2-( 1 -hydroxy-1 -methylethyl) phenyl]propyl-1 -ol]]

142569-70-8


MF: C29H28ClNO2
MW: 457.99

Montelukast

30

AST (S)-2-{3-[3-[2-(7-Chloro-2- quinolinyl) ethenyl]-phenyl]-3- hydroxypropyl} benzoic acid methyl ester monohydrate

287930-78-3


MF: C28H24NO3Cl
MW: 457.96

Montelukast

31

Montelukast DCHA salt Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro- 2-quinolinyl)ethenyl]phenyl]-3- [2-( 1 -hydroxy-1 -methylethyl) phenyl]propyl]thio]methyl]-,compd. with N-cyclohexylcyclohexanamlne (1:1))

577953-88-9


MF: C35H36ClNO3S.C12H23N
MW: 767.6

Montelukast

32

Octahydroindol-2-carboxylic acid (rac. 7aR/3aS/2R, 7aS/3aR/2S)

145438-94-4


MF: C9H15NO2
MW: 169.2236

Trandolapril

33

Benzyl (2S,3aR,7aS)- octahydroindole-2-carboxylate hydrochloride

87679-38-7


MF: C16H21NO2.HCl
MW: 295.80

Trandolapril

34

2-Chloromethyl-3,4- dimethoxypyridine hydrochloride

72830-09-2


MF:C8H11Cl2NO2
MW: 224.08

Pantoprazole

35

5-(Difluromethoxy)-2- [(3-methoxy-4-chloro-2- pyridinyl)methylmercapto]- 1H-benzimidazole

368890-20-4


MF: C15H12ClF2N3O2S
MW: 371.80

Pantoprazole

36

5-(Difluromethoxy)-2- [(3,4-dimethoxy-2- pyridinyl) methylmercapto]-1H-benzimidazole

102625-64-9


MF:C16H15F2N3O3S
MW: 367.37

Pantoprazole

37

2-[[4-(3-Methoxypropoxy)- 3-methylpyridine-2-yl]methylthio]- 1H-benzimidazole

117977-21-6


MF: C18H21N3O2S
MW: 343.44

Rabeprazole

38

6-Chloro-5-(2-chloroethyl) -2-oxyindole

118289-55-7


MF: C10H9Cl2NO
MW: 230.09356

Ziprasidone

39

6-Chloro-5-(2-chloroacetyl)- 2-oxyindole

118307-04-3


MF:C10H7Cl2NO2
MW: 244.07708

Ziprasidone

40

3-Chloro-1,2-benzisothiazole

7716-66-7


MF: C7H4ClNS
MW: 169.63

Ziprasidone

41

3-Piperazinyl-1,2-benzisothiazole hydrochloride

87691-88-1
144010-02-6


MF:C11H14N3ClS
MW: 255.76

Ziprasidone

42

4-[4-(Dimethylamino-1- {4'-fluoro-phenyl) 1 -hydroxybutyl] -3-(hydroxy-methyl benzonitrile (Diol Base)

103146-25-4


MF: C20H23FN2O2
MW: 342.40

Citalopram

43

1-(4-Chlorobenzhydryl)piperazine

303-26-4


MF:C17H19ClN2
MW: 286.80

Cetirizine

44

2-Thiopheneacetyl chloride; 2-(2-Thienyl)acetylchloride

39098-97-0


MF: C6H5ClOS
MW: 160.62

Cephalothine

45

2-Ethoxynaphthalene-1-carbonyl chloride

55150-29-3


MF:C13H11ClO2
MW: 234.68

Nafcillin

46

N-Formyl hexamethylenimine dimethyl acetal

32895-16-2


MF: C9H19NO2
MW: 173.25

Mecillinam Pivmecillinam

47

3,4-Dichloro-alpha methoxy phenyl acetic acid chloride

83833-34-5


MF: C9H7Cl3O2
MW: 253.5

Clometocillin

48

1,1-Cyclohexanediacetic acid mono methylester

60142-94-1


MF:C11H18O4
MW: 214.26

Gabapentin

49

S(+)-2-Aminobutyramide hydrochloride

7682-20-4


MF: C4H10N2O.HCl
MW: 138.60

Levetiracetam

50

Theobromine

83-67-0


MF: C7H8N4O2
MW: 180.16

Pentoxifylline

51

Cyanoacetic acid

372-09-8


MF: C3H3NO2
MW: 85.06

Dextro- methorphan HBr

52

4-(2-Methoxyethyl) phenol

56718-71-9


MF: C9H12O2
MW: 152.19

Metoprolol

53

2-(1-Cyclohexenyl ethylamine)

3393-73-3


MF:C8H15N
MW: 125.21

Dextro- methorphan HBr

54

Dimethyl amine hydrochloride

506-59-2


MF: C2H7N.HCl
MW: 81.55

Metformin, Ranitidine

55

1-Acetyl-4-(4-hydroxyphenyl) piperazine

67914-40-7


MF: C12H16N2O2
MW: 220.27

Ketoconazole

56

4'-Bromomethyl-2- biphenylcarbonitrile

114772-54-2


MF: C14H10BrN
MW: 272.14

Valsartan, Olmesartan

57

1-(6-methylpyridine-3yl)-2- [(4-(methylsulphonyl)phenyl] ethanone [Ketosulfone]

221615-75-4


MF:C15H15NO3S
MW: 289.35

Etoricoxib

58

AABZ 5-Acetoacetylaminobenzimidazol- 2-one

26576-46-5


MF: C11H11N3O3
MW: 233.23

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